Shim-pack GISS Series - Features

HPLC Column Solutions

Column Chemistries
High-speed analysis with ultra-high inertness and high durability

Column Chemistries

	Shim-pack GISS C18
Bonded Phase	Octadecyl Groups
Analysis Mode	Reversed Phase
Features	High-speed analysis with ultra-high inertness and high durability
Particle Size (μm)	1.9, 3, 5
Pore Size (nm)	20
Surface Area (m²/g)	200
Carbon Loading (%)	9
End Cap	○
pH Range	1-10
USP Code	L1

High-speed analysis with ultra-high inertness and high durability

Analysis Examples

■Peaks (100 μg/L each)

	Q1 > Q3
1. Acebutolol	337.10 > 116.05 (+)
2. Atenolol	267.25 > 145.00 (+)
3. Labetalol	329.00 > 161.95 (+)
4. Nadolol	310.05 > 254.00 (+)
5. Pindolol	249.80 > 116.00 (+)

■Conditions

Column	Shim-pack GISS C18 (50 mmL x 2.1 mmI.D., 1.9 μm)
Eluent	A) 10 mM Ammonium Formate in H₂O B) 10 mM Ammonium Formate in CH₃OH A/B = 70/30 ‒ 0.3min - 40/60 ‒ 0.5min - 0/100 ‒ 0.1min ‒ 0/100 ‒ 0.01min -70/30 ‒ 0.5min - 70/30, v/v
Flow Rate	0.6 mL/min
Col. Temp.	40 °C
Detection	LC/MS/MS（ESI, Positive, Negative MRM）

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